By Ivana Pantelic
The on-going ‘green’ development within the own care coupled with worldwide environmental matters, position natural-origin, biodegradable and skin-friendly surfactants reminiscent of alkyl polyglucosides (APGs) in excessive call for. After winning use in cosmetics, adequate facts has been received to welcome a few sugar emulsifiers into the sphere of drug dosage. Alkyl Polyglucosides offers a accomplished compendium which publications a researcher from the APG-related preformulation levels to formula processing, together with the research of varied APG-stabilized platforms epidermis functionality. This booklet introduces a number of APG representatives, their advantages on the subject of convinced traditional surfactants, physicochemical and interfacial houses, attainable interplay with regular parts and various characterization strategies necessary for the evaluation of colloidal platforms. the 1st bankruptcy introduces alkyl polyglucosides, through chapters on their homes, behaviour, an outline of the patent safeguard mechanisms and instructions for filing patent purposes. ultimately, a end surveys foreign patent functions concerning APGs.
- introduces the sector of alkyl polyglucoside emulsifiers, directory the entire modern and newly synthesized APG emulsifiers
- provides distinct info on quite a few facets of APG-based buildings
- reveals power of APG-stabilized cars as potential supply structures utilizing numerous version medications and beauty actives
- includes an up to date overview of study carried out within the box of APGs, facilitating destiny preformulation and formula reports for researchers
- offers a concise and functional compendium of characterization options
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Additional resources for Alkyl polyglucosides : from natural-origin surfactants to prospective delivery systems
As the solid lipid, cetyl palmitate (Cutina® CP, Cognis/BASF, Germany) was used at a concentration of 10% (w/w), while the APGs were used at a concentration of 1% (w/w). , 2011). Aqueous and lipid phases were prepared separately. Solid lipid was melted at 75 °C to prevent the recrystallization of lipids during the process. Hydrophilic surfactants and water were heated to the same temperature and added to the melted lipid phase. The mixture was dispersed with a high-shear mixer (Ultra Turrax, IKA Staufen, Germany) for 30 s at 8000 rpm and subjected to high-pressure homogenization, applying a pressure of 500 bar.
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